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Science

XDF-1 Rescue Serum

30ml

$68.00

E.Q. Discovery Set

120ml

$66.00

XDF-4 After Bite Serum

XDF-4 After Bite Serum targets the visible signs of bug bites with a potent blend of four flavonoids. These powerful plant-derived compounds work to soothe irritation and reduce the appearance of bite marks. Our proprietary XDF technology ensures optimal delivery of these active ingredients, allowing them to penetrate effectively and work where you need them most. Apply directly to affected areas for fast, visible results.

$22.00
  • BENEFITS
  • INGREDIENTS
  • MORE DETAILS
  • Usage

Visibly soothes irritation from bug bites. Helps reduce the appearance of redness and bite marks. Delivers four targeted flavonoid actives directly to the affected area via XDF technology for fast, visible comfort.

Water (Aqua), PEG-40 Hydrogenated Castor Oil, Ethoxydiglycol, Caprylyl Glycol, Glyceryl Laurate, Glyceryl Undecylenate, Xanthan Gum, Phenoxyethanol, Baicalein, Fisetin, Luteolin, Quercetin.

Formulated and manufactured at our Los Angeles facility.

Inspired by the following research:

Kimata M, et al. "Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells." Clinical & Experimental Allergy. 2000;30(4):501–508.

Kim S-H, et al. "Fisetin inhibits IL-31 production in stimulated human mast cells: possibilities of fisetin being exploited to treat histamine-independent pruritus." Life Sciences. 2018;200:22–30.

Park SJ, et al. "Luteolin suppresses IL-31 production in IL-33-stimulated mast cells through MAPK and NF-κB signaling pathways." International Immunopharmacology. 2020.

Kang OH, et al. "Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-κB and MAPKs activation pathways in HMC-1 cells." Molecules. 2010;15(1):385–398.

Weng Z, et al. "Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans." PLoS One. 2012;7(3):e33805.

Cleanse the affected area. Apply a small amount directly to the bite site and allow to fully absorb and dry before layering additional products. For external use only. Discontinue use if irritation occurs. Keep out of reach of children.

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XDF-4 After Bite Serum

$22.00
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