Science
Where pharmaceutical science meets skincare.
Developed by a drug delivery scientist, MARK Los Angeles applies pharmaceutical rigor to skincare. Every formula is built around flavonoids with established mechanisms of action, delivered by our novel XDF™ technology.
XDF™ Transdermal Flavosomes
XDF™ is our novel delivery system, engineered to carry flavonoid actives through the stratum corneum, the skin's primary barrier, to the viable epidermis where they can work. Franz cell testing confirms superior delivery efficiency.
The Science
The Science Behind Every Formula
Each XDF™ product is built around flavonoids with peer-reviewed mechanisms of action and selected for what they demonstrably do at the cellular level, then expertly formulated for delivery.
| Product | Research Objective | Key Mechanism of ACTION |
|---|---|---|
| XDF-1 Rescue Serum | Redness + acne reduction | NF-κB / AP-1 inhibition (EGCG, Quercetin) |
| XDF-2 Lip Health | Defense + lip health | Viral replication interference (5 flavonoids) |
| XDF-3 Density Serum | Hair follicle activation | Wnt/β-catenin activation; 5α-reductase inhibition |
| XDF-4 After Bite Serum | Itch + bite relief | Mast cell stabilization; IL-31 suppression |
| XDF-5 Spot Serum | Targeted acne treatment | C. acnes membrane disruption |
| XDF-6 Barrier | Skin barrier repair | Biomimetic lipid restoration (Ceramide NP) |