Apigenin, Baicalein, Epigallocatechin Gallate (EGCG), Luteolin, Quercetin: Bioactive flavonoids delivering antioxidant activity with established mechanisms of action in skin biology supporting visibly calmer, healthier-looking lips.
Full Ingredients List: Water (Aqua), Hamamelis Virginiana (Witch Hazel) Water (and) Alcohol, PEG-40 Hydrogenated Castor Oil, Ethoxydiglycol, Caprylyl Glycol, Glyceryl Laurate, Glyceryl Undecylenate, Xanthan Gum, Epigallocatechin Gallate, Phenoxyethanol, Luteolin, Quercetin, Baicalein, Apigenin
Powered by patent-pending XDF (Transdermal Flavosomes), a pharmaceutical-grade delivery system designed to bring bioactive flavonoids directly into skin rather than leaving them on the surface.
- 75% delivery efficiency: Franz Cell studies confirm 75% of applied flavonoids reach viable skin layers
- Up to 400× greater penetration than conventional formulations: Independent flux measurements vs. published literature baseline
In stressed human dermal fibroblast studies, XDF-delivered flavonoids demonstrated significant reductions in key markers associated with visible skin inflammation:
- 88% reduction in IL-6
- 99% reduction in IL-8
- 91% reduction in TNF-α
- Complete normalization of reactive oxygenated species (ROS) and C-Reactive Protein (CRP) to baseline levels
These markers are associated with visible redness, irritation, and disruption of the skin barrier. Results are from in vitro studies in stressed human dermal fibroblasts and are not intended to imply clinical efficacy.
In an independent consumer perception study, participants using MARK Lip Health products reported:
- Visibly superior results compared to other lip care products used previously
- Improved visible comfort and reduced visible irritation
- High satisfaction with speed of visible improvement
Apply at the first sign of tingling or irritation. Reapply every 3–4 hours as needed. Follow with Lip Health Balm.
