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Shop plant-based, clinically proven skincare
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EXPERT FORMULATIONS
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VEGAN
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PLANT-BASED
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FRAGRANCE-FREE
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CLINICALLY TESTED
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XDF™ + Plant flavonoids
Nature’s most powerful ingredients, delivered by science.
Flavonoids are nature’s most potent bioactive compounds, renowned for their antioxidant, anti-inflammatory, anti-viral, and anti-bacterial properties. These plant-derived powerhouses play a crucial role in skin health—but their benefits are often lost in traditional skincare due to poor solubility and bioavailability.
MARK Los Angeles transforms flavonoid efficacy with XDF™, our next-generation liposomal delivery system that optimizes flavonoid absorption—maximizing results while minimizing irritation.
Clinically proven results powered by our patent-pending XDF™ delivery system.

A1,24
- Reduced inflammation & redness
- Improved active acne
- Balanced skin health

Sarah, 37
- Reduced breakouts & inflammation
- Improved tone & texture
- Balanced skin health

Dina, 33
- Improved tone & texture
- Reduced breakouts & redness
- Balanced skin microbiome

Redefining skincare with pharmaceutical precision
With a Ph.D. in chemical engineering and over 20 years in drug formulation and delivery, Mark Menning, Ph.D., brings pharmaceutical precision to skincare.
As founder and CEO of MARK Los Angeles, he combines his expertise with a passion for plant-based actives to create safe, effective treatments that deliver results without harsh chemicals—a revolutionary approach to clean, science-driven skincare.
Let customers speak for us
from 96 reviewsI'm a huge fan of the Rescue Serum, so love to see it in a travel size!

I’m in love with the Mark Los Angeles moisturizer! A little goes a long way, so it’s definitely worth the investment. Just a small amount provides deep hydration that keeps my skin feeling soft and plump throughout the day. It’s lightweight, non-greasy, and absorbs beautifully, leaving my face feeling nourished without any heaviness. I’ve noticed that my skin feels firmer and looks healthier since I started using it. In fact, it has extended the interval between my botox treatments! What I love most is that it’s made with clean ingredients—this is important to me, and it gives me peace of mind knowing I’m putting something pure on my skin. This moisturizer has become an essential part of my daily routine and will continue to be!

This light moisturizer feels like it was custom made for my ultra sensitive skin. It is lightweight yet provides ample moisturizer so my skin doesn't feel tight. It doesn't cause any redness or stinging. The 3 main ingredients are perfect for our hot and humid climate in the deep south They are squalane, jojoba oil and coconut triglycerides. All of which are soothing and hydrating. Highly recommend!
Was looking for a good daily moisturizer to add to my routine. This one from Mark Los Angeles uses premium ingredients, plant-based, and packed with plant flavonoids, quersetin, jojoba oil, and coconut triglycerides. It feels really good on my skin. It doesn’t weigh it down or clog my pores. Builds a nice moisture barrier. I do feel it reduced inflammation and redness on my sensitive skin. Made in USA. 🇺🇸
This exfoliating cleanser is pretty good. It has very fine particles in it that exfoliate gently and gradually so it doesn't cause irritation or redness. It doesn't suds up much but it definitely made my skin cleaner and smoother. I also like the glass bottle this came in. It has a sturdy pump top with a pump protector so it was well sealed - there was no leakage enroute unlike with other liquids I have gotten on Amazon. This was expensive for a facial cleanser but if it comes with a good coupon it is worth getting.

This EQ Exfoliating Cleanser by Mark Los Angeles is a high quality cleanser that is plant based with squalane, EGCG, quercetin and other antioxidants. I love that it is basically unscented and that it is made in the USA! The exfoliant that is used in this product are walnut shells instead of plastic beads which is so much better for the environment. The exfoliant is mild but feels very effective. My face feels very clean and not too dried out after using. I like that the consistency of this is more of a cleanser versus an exfoliant as I feel I could use this twice a day with no issues. Sometimes exfoliants are too thick and gritty and you only can use it every few days because of that. Not with this product! The glass bottle makes this cleanser feel very high end and the pump is easy to use and close for travel with the included safety cap. My husband and teen daughter has also tried this cleanser out and loved how clean it made their skin. Now I just need to hide it from them so they don’t keep using it. Highly recommended!

Some days, I need something very simple and gentle to cleanse all the sunscreen and makeup off my sun- and wind-irritated face. I work outdoors, which can be very rough on skin, but am diligent about caring for it.
I've tried many cleansers. On heavy SPF days, many can't get all the residue off. Some have too much graininess and feel like they're taking some of my actual skin off with the residue. This cleanser is right in the middle. I can feel the exfoliating granules (which are made from walnut shells--no microplastics here!) but there are not too many of them, and they are softer-textured and smaller than those heavy exfoliants from the 90s.
I appreciate the short, simple ingredient list; I'm picky about what I put in and on my body. This would work well for more sensitive skins. No heavy fragrance. After washing, my skin felt clean and free of sunscreen residue, but not stripped, dry, or tight.

The E.Q. Exfoliating Cleanser works really well on my aging skin. Every now and then, I might get a breakout, so I need something that helps keep them under control or, better yet, prevents them altogether. It’s super easy to get the cleanser out of the bottle, and I like that just a small amount lathers up nicely, leaving my skin feeling really clean. After using it with my favorite toner, I’ve noticed fewer dark spots on my face, which is a big plus. The scent is so relaxing—it makes my skincare routine feel like a little treat. I love that it’s made with plant-based ingredients because it doesn’t dry out my skin at all. And the dark bottle? A smart touch since it helps protect the product from light. This has definitely become my go-to when I need that extra-deep clean feeling.

This is an exfoliating cleanser by MARK Los Angeles.
The box says "ECGC + Quercetin" as key ingredients, but it also has squalane oil and castor oil. It uses walnut shells for exfoliation.
It goes on like any other comparable cleanser and it does a decent job of making the face feel clean and refreshed. The plant based ingredients are a plus for me, and I like the minimal list of ingredients to get a viable product.
I had no redness or irritation after using this and I'd say my skin is normal and perhaps a bit sensitive.
Overall, this is an effective cleanser and I have made it a part of my beauty ritual.

This is a nice smooth gel cleanser with gentle exfoliation beads. It cleans well and causes no sensitivity issues. My hubby and I are both using it, and it works well for my dry sensitive skin and his tough oily skin. Highly recommend for all skin types.

E.Q. Rescue Serum feels great going on, and I feel like it makes my skin feel more firm and lifted. It’s also more smooth, moisturized and healthy looking. Initially this product appealed to me for its unique anti-inflammatory properties and it’s truly remarkable how quickly I noticed dramatic improvements in radiance & texture. Plus, the packaging is beautiful & the bottle design makes it super easy to use the right amount of product. I love using this product both day and night - it works well both under other products & makeup. I use it with products from MARK and other brands and am overall so happy with the efficacy.

The E.Q. Rescue Serum has been a wonderful addition to my skincare routine. It has a lightweight, non-greasy formula that absorbs quickly, leaving my skin feeling refreshed and hydrated. With consistent use, I’ve noticed a reduction in redness and fewer blemishes. It's gentle and works well under makeup, making it easy to incorporate daily. A great option for those looking to calm and clarify their skin!

Now let me just say me and my daughter love this product and we where both skeptical about it
Bit no it's true it truly tarted clearing my daughter's face up after one use no joke and her face is looking great after 3 uses but not completely clear yet and why I love it well I found that it makes my wrinkles disappear every use and it's like it softens the skin and my wrinkles just fall right off so I put it on rub it in then let it dry the pull and there gone well I pull a few times if it's not completely gone but it really works and it is sticky at first but give it a few seconds to dry and smooth skin no sticky residue but seriously this is a wonderful product but it does have a big price tag but you only need a tiny amount to so it will last a minute
And it does dry mat so no glossy look or greasy.
So yes it truly does what it says and I can't be happier with it.

I had a blemish and applied the product on early in the morning. When I got back home from work I did not see any redness and it appeared to be on the mend much quicker than other products that I've used. It is different as the viscosity is thicker than most oils. Overall, I'm please with this product.


The E.Q. Clear Skin Collection
Reduce blemishes and redness, improve skin texture, and renew the look of beautiful skin with our transformative, clinically-tested formulas infused with powerful plant flavonoids.